【Introduction】Hericium erinaceus, is a rare traditional Chinese dishes. Since the 1970s, the clinical application showed Hericium treat indigestion, ulcers, gastric inflammation, stomach pain, bloating, and neurasthenia and other diseases. For patients with mild neurasthenia, Hericium can act as adjuvant therapy. In the clinical application, the usage of Hericium treatment for mild or severe neurasthenia can get the desired effect.